Despite playing away, Hoang Anh Gia Lai created a lopsided game throughout the 90 minutes of play.
Hong Duy opened the scoring for the V.League club with his brilliant personal attempt in the 27th minute.
The guests came close to doubling their advantage just one minute later as Minh Vuong drove a penalty kick over the crossbar.
However, Minh Vuong promptly redeemed himself eight minutes after the break, converting a pass from Van Toan into a second goal for the Gia Lai team.
With time running out, the home side fought back strongly seeking to narrow the deficit; however, lack of accuracy in their final attempts prevented them from earning even a consolation goal.
In another match on the same day, SHB Da Nang bid farewell to their National Cup campaign after losing 0-1 to Hai Phong FC.
Da Nang players created a number of chances to score, but the wastefulness of opportunities cost them dearly, as Fagan scored the match’s solitary goal a few minutes from full-time to seal a round of 16 place for Hai Phong.
Ho Chi Minh City also made it through to the round of 16 following their 2-1 victory over Pho Hien FC on Sunday.
Hoang Thinh put HCM City ahead after just three minutes, only to see his efforts cancelled out six minutes later as Xuan Nam successfully converted a penalty.
Van Thanh restored the lead for the HCM City side eight minutes later, which was enough to secure them a berth in the round of 16.
Results of other qualification matches:
Dong Thap 3-4 Tay Ninh
Khanh Hoa 0-2 An Giang
Saigon FC 6-1 Binh Dinh
Binh Phuoc 2-2 (Pen 8-7) Can Tho
Long An 1-1 (Pen 3-5) Nam Dinh
Phu Dong 0-1 Quang Nam