Ebola emergency turns spotlight on experimental drugs

With hundreds of patients in Africa suffering the devastating effects of Ebola, health experts are scrambling to determine which drugs might offer the best experimental treatment, and researchers are being pressed by government officials to speed up their work.

A health worker, wearing personal protection gear, offers water to a woman with Ebola virus disease (EVD), at a treatment centre for infected persons in Kenema Government Hospital, in Kenema, Eastern Province, Sierra Leone in this August, 2014. (Credit: Reuters/Dunlop/UNICEF)
A health worker, wearing personal protection gear, offers water to a woman with Ebola virus disease (EVD), at a treatment centre for infected persons in Kenema Government Hospital, in Kenema, Eastern Province, Sierra Leone in this August, 2014. (Credit: Reuters/Dunlop/UNICEF)

Three treatments have shown especially promising results in monkeys, the researchers said. One, produced by tiny California biotech Mapp Biopharmaceutical, gained international prominence this week when it was given to two U.S. aid workers who contracted Ebola in West Africa and have since shown signs of improvement.

Others are from Vancouver-based Tekmira Pharmaceuticals and privately-held Profectus BioSciences, of Tarrytown, NY.

On August 6 the World Health Organization said it would discuss next week the ethics of using Ebola drugs that have never been cleared for human use, wary of a long history of medicines being tested on people who were never properly informed of the risks. In the countries hardest hit by Ebola, suspicion of foreign medical workers is already widespread.

REUTERS