The index closed 0.87 points lower, after gaining 2.84 points yesterday.
Trading on the Ho Chi Minh Stock Exchange (HoSE) fell by 6.97% to VND10.89 trillion ($463.80 million).
Foreign investors were net sellers to the tune of VND 332.06 billion, mainly selling VHM of property giant Vinhomes and VND of brokerage VNDirect.
The HNX-Index at the Hanoi Stock Exchange, where mid and small-caps list, was up 0.40%, while the UPCoM-Index at the Unlisted Public Companies Market was down by 0.16%.