A train loaded with auto parts and office equipment departed from the Henggang Railway Station in Nanchang on the day, marking the launch of the service.
The total length of the route is over 1,700 kilometres, passing through Pingxiang city in the Guangxi Zhuang Autonomous Region, before crossing the border into Vietnam.
The journey will take around five days, 15 days less than the original route by sea and the cost is only half of that of road transport.
The train service will become regular next year.
The new service is expected to promote economic and trade cooperation between landlocked Chinese provinces, such as Jiangxi, with Southeast Asia.
